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A related study developed an ex vivo fixation technique to preserve the native transcriptomic state of MuSCs, revealing that conventional isolation methods induce transcriptional and epigenetic artifacts and identifying novel quiescence-associated markers such as HOXA9

doi: 10.1084/jem.20180199 54 LawrenceT

Reduced appetite , which, while a therapeutic goal, may sometimes result in inadequate caloric intake if not monitored

in these cases, withdrawal starts a day or two after cessation, has a peak of a week or more, and can persist for as long as 2 to 3 weeks

Although research continues, healthcare providers emphasize that treatment decisions should always be individualized