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Mutated iPSCs and an isogeneic control were differentiated into hepatic (HPC), mesenchymal (MPC) and endothelial (EPC) progenitor cells and used to compose the liver organoids

doi: 10.1021/jf203428t

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Physical examination typically reveals cyanosis, particularly at the nail beds, ears, and lips, alongside clubbing fingers

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Disease recurrence was seen in all six subjects who underwent follow-up endoscopy at 6 months after reintroducing all food groups