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Pharmacology of testosterone replacement therapy preparations

In individuals with PLPBP mutations, the most common metabolic abnormality is an increase in blood lactate and glucose levels, leading to metabolic acidosis shortly after birth, typically on day 1, then returns to normal by day 3 to 4 [11]

This ensures maximum local concentration [21]

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Another way is to take drugs that change the brain signaling pathways in our hypothalamus so that our bodies convince themselves they need to produce less testosterone to thrive