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Where evidence is anecdotal or practitioner-derived, it is labelled as such

Groups that may benefit include: Individuals with high energy demands due to work or exercise Those following vegan or vegetarian diets, which can be low in B12 Older adults, as B12 absorption can decrease with age B12 and Folic Acid Combination Injections Healthcare providers might suggest combination injections for low B12 and folic acid levels

Nat Rev Dis Primers (2017): Vitamin B12 is essential for normal nervous system function via its role in myelin synthesis and for circulatory system function through its role in red blood cell maturation in the bone marrow

The condition is more likely to occur in older people due to the cutback in stomach acid production that often occurs with aging

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