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However, its ability to cause infection drops dramatically over time

Dynamic disulfide exchange in a crystallin protein in the human eye lens promotes cataract-associated aggregation

Furthermore, reduced levels or inhibition of USP1 resulted in decreased expression of several BMAL1 target genes, including CRY1, CRY2, PER1, PER2 , and DBP , along with reduced protein levels of BMAL1, CRY1, and CRY2 ( Interestingly, USP1 displays a strong tissue-specific expression

Involvement of TCF7L2 in generation of morphine-induced antinociceptive tolerance and hyperalgesia by modulating TLR4/NF-B/NLRP3 in microglia

This comprehensive review brings together multiple lines of evidence for the dysfunction of the glutamate system in mood disorders, including genetic, post-mortem and in vivo neuroimaging data