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doi: 10.1111/ppl.13012 55 KayaC.OkantM.UgurlarF.AlYemeniM

However, several limitations may preclude the use of Fer-1 and Lip-1 in clinical settings, including their possible unsatisfactory pharmacokinetics and pharmacodynamics profiles

All experimental protocols were approved by the University of Virginia IACUC on 04/22/2019 (protocol n: 4269)

It is a potent antioxidant that plays a crucial role in detoxification, immune function, and combating oxidative stress

For example, PHGDH is overexpressed in glioma and stabilises the transcription factor, FOXM1, leading to increased expression in genes that promote tumour invasion, angiogenesis, and regulate the cell cycle (Liu et al, 2013)