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Beyond its role in interbacterial competition and microbiota modulation, T6SS also contributes to immune evasion by delivering effector proteins into host cells, such as the VgrG4 effector, which induces mitochondrial fragmentation and activates immune modulators like NLRX (Liu et al., 2023)

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References Scales CD Jr, Smith AC, Hanley JM, Saigal CS

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Jr Iron, zinc, and alcohol consumption and mortality from cardiovascular diseases: the Iowa Womens Health Study