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J Physiol 599(23):51635177 Ayari S, Abellard A, Carayol M, Guedj E, Gavarry O (2023) A systematic review of exercise modalities that reduce pro-inflammatory cytokines in humans and animals models with mild cognitive impairment or dementia

They are divided into four groups: one group is given Treosulfan (1.5 g/kg/day) for 3 consecutive days , one group receives NSC-26271 (0.1 g/kg/day) for 2 consecutive days, one group is treated with liposomal NCI C01592 (37 mg/kg/day) for 4 consecutive days, and there is a control group with no treatment

Various study on IGF-1R, IGF-1 and IGF-2 expressions reported findings usable for useful patient stratification in future trials with inhibitors of the IGF-1R signaling pathway, to sort out those that may benefit the most from anti-IGF-1R therapies, limiting exposure of other patients to these agents (62, 63)

Limitations and gaps in the current evidence Several limitations constrain interpretation of the current evidence base

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Regulation of cellular glutathione