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GABA A receptors are ionotropic chloride channels (Enna, 2007), while GABA B are metabotropic G-coupled protein receptors (GPCR) (Pinard et al., 2010)

Flavonoids, for example, are phenolic chemical derivatives that can bind RONS, restrict the operation of enzymes that make RONS, and form chelates with metals that stimulate the synthesis of RONS, preventing RONS interactions with normal cells such as lipid peroxidation and DNA damage