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(131) demonstrated that supplementing with Lachnospiraceae bacterium strains significantly alleviated neutrophil infiltration and oxidative stress in ethanol-exposed mouse livers, exhibiting remarkable hepatoprotective effects

However, their contribution is context-dependent, as genetic ablation of ABCC1 does not fully prevent apoptosis-associated GSH loss in certain models 43 , indicating the existence of compensatory or alternative efflux mechanisms

With regard to haemolymphatic cells, they represent the first line of defence against pathogens and xenobiotics and can be considered suitable biomarkers for monitoring the effects of environmental stress ( M

At the same time, it is also involved in the up regulation of adhesion molecules and the release of proinflammatory Th2 cytokines such as IL-4, IL-5 and IL-13