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Plasma concentration of the astrogliosis marker, GFAP, was also increased in patients with moderate to severe COVID-19 (Kanberg et al

Make sure to do a patch test first

2021).The propensity for lipoxidation depends on the abundance, reactivity, as well as accessibility of the nucleophilic sites of proteins (Martin-Sierra et al

Recent studies have demonstrated that optimizing trace mineral nutrition can improve the productive performance and physiological status of ducks, and the enhanced bioavailability of nano-trace minerals may further increase their biological efficiency 31

Many nutraceuticals (Campos et al ., 2019), food supplements (Matera et al ., 2023), and pharmaceutical prescriptions (Raut and Karuppayil, 2014) are explored and manufactured based on the bioactivities of EOs

However, in OA, M2 numbers are limited and may shift toward an M1-like phenotype under sustained inflammatory stimuli, reducing their capacity to maintain iron homeostasis (109, 110).Together, these insights support the hypothesis that iron metabolism in M1 macrophages not only contributes to ferroptosis susceptibility in OA, but also represents a potential immunometabolic checkpoint for therapeutic intervention