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When the protein folding capacity of the endoplasmic reticulum is overwhelmed, it triggers an unfolded protein response that, if prolonged, can lead to inflammation and the apoptosis of insulin-producing cells and insulin resistance

Therefore, publication bias is unlikely to have a major impact on the overall findings of this meta-analysis

Children with RS grow slower than typically developing children [364]

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EMBO J 22 : 53905402 Bharti A, Ma PC, Maulik G, Singh R, Khan E, Skarin AT, Salgia R (2004) Haptoglobin alpha-subunit and hepatocyte growth factor can potentially serve as serum tumor biomarkers in small cell lung cancer