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This treatment significantly ameliorated doxorubicin-induced testicular weight loss, decreased sperm concentration and motility, and reduced abnormal sperm rates, ultimately attenuating doxorubicin-induced degenerative changes in seminiferous tubules

A patch test is often performed to ensure safety before proceeding

Acta 1851 , 9991005 (2015)

doi: 10.1136/thoraxjnl-2018-212557 26 DanelishviliL.EvermanJ

The protective benefits of Mn porphyrins, including MnTM-2-pYp 5+ , MnTDE-2-ImP 5+ and MnTE-2-pYp 5+ , have been established in animal models of several diseases, including sickle cell disease [204], radiation induced injury [205], breast cancers [206], diabetes [207]