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Furthermore, SAMe is able to modulate the levels of certain lncRNAs altered in HCC, which have been proposed as biomarkers of liver cancer progression [241]

In the animal studies, one-way ANOVA with Dunnetts multiple comparisons tests were used to assess significance in weight changes and viral loads across groups compared to the isotype control antibody-treated animals

A mother-to-infant model is developed to mimic the infant feeding pattern and used to predict their drug exposures

Emerging innovations include stimuli-responsive delivery systems that release STING agonists in response to TME characteristics (acidic pH, hypoxia, ROS, specific enzymes), enabling precise spatiotemporal control of immune activation (163, 164)

Dermatol 127 (11), 25582562

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