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Mechanistically, LT intervention successfully reconstituted the ovarian angiogenic milieu in PCOS mice by concurrently inhibiting VEGFA-VEGFR2-mediated pathological angiogenesis and MMP2/9-dependent extracellular matrix remodeling

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FcRn-ligand complexes are instead sorted into vesicles that traffic back to the plasma membrane and undergo exocytosis 42,43,44,45,46,49

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Thus, both immune and non-immune cells are closely involved in this process, while their interplays are not fully understood

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