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In DR, most histone modifications serve as negative regulators of the antioxidant defense system in retinal cells

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Atta AH, Soufy H, Nasr SM, Soliman AM, Nassar SA, Al Maweri A, Abd El-Aziz TH, Desouky HM, Abdalla AM

Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways